Pregnant women have an increased risk of infectious diseases, including respiratory infections such as influenza, and are included on the coronavirus disease 2019 (COVID-19) UK clinically vulnerable list. Little is known about the risk of COVID-19 to unborn children, with data limited to a case series of 3 stillbirth deliveries in pregnant women with confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and a single London hospital reporting a higher rate of stillbirth deliveries during the pandemic period compared with a prepandemic period. To provide more robust data, we used national and regional hospitalization data in England to assess the risk of stillbirths during the COVID-19 pandemic.
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has had far-reaching implications, including changes in societal stressors and health care delivery, which may alter preterm birth risk. Previous studies in the US regarding SARS-CoV-2 in pregnancy focused on associations of SARS-CoV-2 infection with cesarean delivery, neonatal transmission, preterm birth, and stillbirth. In a relatively homogeneous Danish population, Hedermann et al reported a decrease in preterm birth during the pandemic among uninfected patients. Given differences in preterm birth across populations, we examined a diverse urban cohort in the US to determine if preterm birth, spontaneous preterm birth, medically indicated preterm birth, and stillbirth rates have changed during the SARS-CoV-2 pandemic.
2 исследовательские статьи в
JAMA
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